The Center for Drug Discovery NMR Facility has a 700 MHz 4-channel NMR spectrometer equipped with 4 variable temperature multinuclear probes and gradient capabilities and operating both in solution and solid-state modes is capable of carrying out all modern one- and multi-dimensional experiments. The CDD also has a 400MHz 4-channel wide-bore spectrometer dedicated to solid-state NMR experiments and also available for solution experiments that allows us to run the most advanced Rotational Echo Double Resonance (REDOR) and double REDOR experiments.